Effect of glutamine supplementation combined with resistance training on muscular performance, body composition and protein degradation
Year: 2000
Type: dissertation
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: The purpose was to assess the effect of oral glutamine supplementation combined with resistance training in young adults.Thirty-one subjects, aged 18-24, were randomized (double blind) to receive glutamine (0.9g/kg lean tissue mass; n=17) or placebo (0.9g/kg lean tissue mass; n=14) during 6 weeks of total body resistance training.Exercises were performed for 4-5 sets of 6-12 repetitions at intensities ranging from 60-90% 1-RM.Before and after training, measures were taken for !-repetition maximum squat and bench press strength, peak knee extension/ flexion torque (Biodex isokinetic dynamometer), lean tissue mass (dual energy X-ray absorptiometry) and muscle protein degradation (urinary 3-Methylhistidine by high performance liquid chromatography [HPLC]).Repeated measures ANOV A showed that strength, torque, lean tissue mass and 3-Methylhistidine increased with training (p<0.05), with no significant difference between groups.Both groups increased their 1-RM squat by 30% and 1-RM bench press by 13 .5%.The glutamine group had increases of 6% for knee extension torque, 5% for knee flexion torque, 2% for lean tissue mass and 41% for 3-Methylhistidine excretion.The placebo group increased knee extension torque by 2%, lean tissue mass by 1. 7% and 3-Methylhistidine by 56%.However, knee flexion torque decreased by 2%.We conclude that glutamine supplementation during resistance training has no significant effect on muscular performance, body composition or muscle protein degradation in young healthy adults.
Author: Darren G. Candow
Language: English
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1534447853