Mutations located on both F1 and F2 subunits of the Newcastle disease virus fusion protein confer resistance to neutralization with monoclonal antibodies
Year: 1989
Type: article
Abstract: The fusion gene sequence of six Newcastle disease virus escape mutants revealed that residues important for the integrity of antigenic site 1 and antigenic site 2 were located, respectively, on the F2 subunit and within the cysteine-rich domain of the F1 subunit. We further report the antibody-binding capacity of these mutants.
Source: Journal of Virology
Authors: C Neyt, J Geliebter, M Slaoui, D Morales, G Meulemans, A Burny
Institutions: Université Libre de Bruxelles, Vrije Universiteit Brussel
Language: English
Topic: Virology and Viral Diseases
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1539173781