Work

Oligonucleotide-modified Nuclotides

Year: 2013
Type: dissertation
Abstract: Modified nucleotides are interesting tools: They can alter the characteristics of DNA in many ways and enable the applicability of DNA in several innovative biotechnological applications. The first part of this thesis contributes to a better understanding of the acceptance and incorporation mechanism of modified nucleotides by DNA polymerases. Therefore modified nucleotides were successfully synthesized and incorporated into DNA by diverse DNA polymerases.
Language: English
Open Access status: green
OpenAlex ID: W154036890
Cites: 173
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Related to: 10