Adenine Nucleotide Transport in Submitochondrial Particles and Reconstituted Vesicles Derived from Bovine Heart Mitochondria
Year: 1974
Type: article
Abstract: Uptake of ATP by submitochondrial particles from bovine heart was stimulated 15-fold by internal ADP. The transport was inhibited by atractyloside and bongkrekic acid. Vesicles prepared with soybean phospholipids and a protein fraction from mitochondria also catalyzed the ADP-dependent and inhibitor-sensitive uptake of ATP. This reconstituted system provides a suitable assay for the purification of the mitochondrial adenine nucleotide carrier.
Source: Journal of Biological Chemistry
Authors: Howard G. Shertzer, Efraim Racker
Institution: Cornell University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W1541819535
