Year: 2009
Type: dissertation
Abstract: In developed countries, prostate cancer is the most common malignancy in men and a\nmajor cause of cancer-related death (1). In The Netherlands 93 new cases per 100,000\nmen were detected in 2003 (The Netherlands Cancer Registry). Prostate cancer incidence\nvaries between different ethnic groups. African-American men have the highest\nincidence rates, followed by Caucasian-American men and men in Western Europe\nand Australia. The lowest incidence rates are observed in the Asian population. These\ndifferences may be explained by environmental and dietary factors. However, genetic\nfactors, i.e. polymorphisms in genes that can predispose to cancer, may also play a role\nin prostate cancer development. A major risk factor of prostate cancer is age, since it is\npredominantly a disease of the senior adult (i.e. men over the age of 65 years). Below the\nage of 55 the incidence of prostate cancer is very low (2, 3).
Author: Karin G. Hermans
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1542691931