Geometry of Protein Structures. I. Why Hyperbolic Surfaces are a Good Approximation for Beta-Sheets
Year: 2004
Type: article
Abstract: . Protein structure is invariably connected to protein function. To analyze the structural changes of proteins, we should have a good description of basic geometry of proteins ’ secondary structure. A beta-sheet is one of important elements of protein secondary structure that is formed by several fragments of the protein that form a surface-like feature. The actual shapes of the beta-sheets can be very complicated, so we would like to approximate them by simpler geometrical shapes from an approximating family. Which family should we choose? Traditionally, hyperbolic (second order) surfaces have been used as a reasonable approximation to the shape of betasheets. In this paper, we show that, under reasonable assumptions, these second order surfaces are indeed the best approximating family for beta-sheets. Introduction. Proteins are biological polymers that perform most of the life’s function. A single chain polymer (protein) is folded in
Authors: Boguslaw Stec, Владик Крейнович
Institution: The University of Texas at El Paso
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Awards: MRI: Acquisition of Equipment to Support Collaborative, Multi-Disciplinary Research and Development of Reliable Software, ITR Collaborative Research: GEON: A Research Project to Create Cyberinfrastructure for the Geosciences, ITR/IM+AP(GEO)Collaborative Project-Creation of a Geospatial Data System for the Transition Zone Between the Colorado Plateau and Basin & Range Provinces (Geoinformatics in Action), PAN AMERICAN CENTER FOR EARTH AND ENVIRONMENTAL ST
OpenAlex ID: W1543492754