Work

Structure and Function of the Hepatitis E Virus Capsid Related to Hepatitis E Pathogenesis

Year: 2011

Type: book-chapter

Abstract: ORF3, which partially overlaps with the other 2 ORFs, encodes a 13.5kDa regulatory phosphoprotein with multifunctions (Monga, 2011;Vasickova et al., 2007).Due to the lack of a robust cell culture system, the viral structural studies have mainly relied on recombinant capsid protein (CP) from in vitro cell expression (Li et al., 2005;Li et al., 1997).Recent findings from HEV expression and purification, X-ray crystallography, and electron cryomicroscopy (cryoEM) have begun to shed new light on the structural and functional properties of this important human pathogen. How to referenceIn order to correctly reference this scholarly work, feel free to copy and paste the following:

Source: InTech eBooks

DOI: 10.5772/27635

Authors: Zheng Liu, Yizhi Jane, Jingqiang Zhang

Institutions: Sun Yat-sen University, Rice University

Language: English

Topic: Hepatitis Viruses Studies and Epidemiology

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W1543797957