Work

Insights into the pathogenesis of NAFLD: The role of metabolic and pro-inflammatory mediators

Year: 2009

Type: article

Abstract: Non alcoholic fatty liver disease (NAFLD) is a part of the metabolic syndrome which also comprises obesity, dyslipidaemia, type 2 diabetes mellitus and hypertension. The importance of NAFLD is due to its high prevalence and its potential to evolve into cirrhosis and hepatocellular carcinoma. In recent years several molecular pathways have been shown to be involved in this syndrome. Moreover the role of many cytokines has been elucidated. In the present review we discuss the recent evidence regarding the role of metabolic and proinflammatory mediators in the pathogenesis of NAFLD.

Source: UCL Discovery (University College London)

Authors: Elias Xirouchakis, Pinelopi Manousou, Lemonia Tsartsali, S Georgopoulos, Andrew K. Burroughs

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W1544105087

FWCI:

Cites: 77

Cited by: 7

Related to: 10