Work

Inhibitory effects of different lactobacilli on Candida albicans hyphal formation and biofilm development.

Year: 2014

Type: article

Abstract: The aim of this study was to investigate the effects of different species of Lactobacilli on hyphal formation and biofilm development by the opportunistic fungal pathogen Candida albicans. We employed 4 different Lactobacillus species, namely L. rhamnosus, L. acidophilus, L. plantarum and L. reuteri, and 2 C. albicans strains, the reference DAY286 and its isogenic hwp1/hwp1 mutant, the FJS24 strain. As assessed by morphological analysis and quantitative colorimetric assays, Lactobacillus crude filtrate supernatant fluids (CFSF) affected Candida, impairing both hyphal formation and biofilm production. The CFSF-mediated phenomenon occurred in a dilution- and time-dependent manner and was consistently observed, irrespective of the C. albicans HWP1 genotype.

Source: PubMed

Authors: C F Orsi, C Sabia, A Ardizzoni, B Colombari, R G Neglia, S Peppoloni, G Morace, E Blasi

Institutions: University of Milan, University of Modena and Reggio Emilia

Language: English

Topic: Probiotics and Fermented Foods

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1544205114

FWCI: 3.687

Cites:

Cited by: 37

Related to: 10