Work

RNA virus quasispecies populations can suppress vastly superior mutant progeny

Year: 1990

Type: article

Abstract: A variant clone of vesicular stomatitis virus recovered from a high-passage, evolving virus population replicated rapidly and produced remarkably high yields of virus, but these variants never dominated during further passages. We show that this clone is highly competitive, but it can overwhelm its progenitor population only when seeded above threshold level during dilute passages.

Source: Journal of Virology

DOI: 10.1128/jvi.64.12.6278-6281.1990

Authors: J C de la Torre, J J Holland

Institution: University of California San Diego

Language: English

Topic: Evolution and Genetic Dynamics

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Award: G515652837