Primary Sequence of U-1 Nuclear Ribonucleic Acid of Novikoff Hepatoma Ascites Cells
Year: 1974
Type: article
Abstract: The U-1 RNA is one of the low molecular weight nuclear RNAs of Novikoff hepatoma ascites cells that is specifically localized to the extranucleolar portion of the nucleus. After the RNA was purified by polyacrylamide gel electrophoresis, it was subjected to various enzymatic digestion procedures for determination of its primary nucleotide sequence. The U-1 RNA contains 171 nucleotides. Its 5′ end is an alkali-stable tetranucleotide containing N2,2,7-trimethyl guanylic acid. The primary sequence of U-1 RNA is: (m32,2,7G, Am, Um) [see PDF for sequence]
Source: Journal of Biological Chemistry
Institution: Baylor College of Medicine
Language: English
Topic: RNA Research and Splicing
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W1555556483