The Combination of Smoking and Overweight is Associated with Dyslipidemia Among Inpatients and Hypertension Among Outpatients with Schizophrenia
Year: 2011
Type: article
Study design: Observational Study
Abstract: SUMMARYObjective:As the physical health of patients with schizophrenia is relatively poor and their risk of prematuredeath is considerably increased compared with the general population, we examined the associationbetween lifestyle-related diseases and smoking, drinking, and overweight in inpatients and outpatients withschizophrenia.Methods:The study design was cross-sectional. Subjects were 138 inpatients and 135 outpatients withschizophrenia from a psychiatric hospital in Japan. They were asked for information concerning smokingand alcohol use, and height and weight were measured to calculate body mass index. Data on hypertension,dyslipidemia, type 2 diabetes, cardiovascular diseases, and use of atypical antipsychotics were acquired frommedical records.Results:Inpatients were more likely to receive atypical antipsychotic medication and less likely to drinkalcohol. The smoking prevalence was 38.4% (53.8% in men, 17.2% in women) in inpatients and 39.3%(56.3% in men, 20.3% in women) in outpatients. Multivariate odds ratio( OR) for hypertension was significantlyhigher among outpatients than inpatients. After adjustment for age, sex, and use of atypical antipsychoticmedication, overweight smokers showed a significantly higher OR for dyslipidemia (3.17, 95% CI:1.07-9.37) among inpatients, and a significantly higher OR for hypertension (3.15, 95% CI:1.14-8.74)among outpatients. When the reference group is non-smokers with BMI below 25, smokers with BMI of 25or more had a significant higher OR( 3.38, 95% CI:1.36-8.38) for dyslipidemia among patients with schizophrenia.Conclusion:After adjustment for atypical antipsychotic medication use, the combination of smoking andoverweight was significantly associated with the prevalence of dyslipidemia among inpatients and hypertensionamong outpatients with schizophrenia.
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W155846435