Year: 2014
Type: dissertation
Abstract: As our life expectancy continues to rise, the prevalence of diseases associated with aging increases correspondingly. For Alzheimer’s disease, this implies that the number of persons affected, directly or indirectly, will rise dramatically. Early diagnosis, intervention, and ultimately prevention of Alzheimer’s disease are therefore ever more urgent research aims. Advanced neuroimaging techniques such as diffusion MRI, which provides non-invasive insight into brain changes at the microstructural level, are promising for the identification of changes that relate to the early stages of the disease. Disentangling these early pathological changes from those in ‘normal’ brain aging however requires more insight in the broad spectrum of
Author: Marius de Groot
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1560910129