Year: 2011
Type: book-chapter
Abstract: Classification of pulmonary amyloidosisAmyloid in the respiratory tract has been classified by authors at The Mayo Clinic as associated with systemic amyloidosis and localized pulmonary disease.(Utz et al., 1996) The most common cause of the respiratory amyloid disease is secondary to systemic AL Amyloidosis which accounts for up to 80% of pulmonary amyloid.(Pitz et al., 2006) Moreover, it has been reported that 88% of patients with systemic amyloid have pulmonary disease.(Smith et al., 1979) Amyloidosis localized to the respiratory tract was first recognized by Lesser in 1877.(Lesser, 1877) Amyloidosis at present is best classified by the protein fibrils and then by the location of sites involved clinically.To date, there are 27 known extracellular fibril proteins identified in humans.Table 1 lists some of the common protein subunits.Clinically there are three broad classifications of pulmonary involvement.The amyloid deposition may predominantly www.intechopen.com
Source: InTech eBooks
DOI: 10.5772/23776
Authors: Mark E., Priya Bakaya, Jeffrey B.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W1562646593