Year: 2014
Type: article
Abstract: Chronic use of various recreational drugs is leading to drug abuse which is increasingly developed in the modern society among the various populations throughout the world. The present study was conducted to investigate the impact of a few recreational drugs viz., anabolic androgenic steroids (AAS), alcohol and nicotine on male fertility status which was assessed by measuring sperm count in male albino mice. Semen samples were collected from normal, AAS-treated, alcohol-treated and nicotine-treated mice and the sperm count (in millions/ml semen) was assessed at regular intervals i.e. on 10th, 20th, 30th, 45th,60th,75th and 90th day of treatment during the experimental period of 90 days. The results showed a significant decrease in the sperm count in AAS-treated, nicotine-treated (p<0.01) and alcohol-treated mice (p<0.05) compared to that of the normal mice. The present study clearly indicates suppression of sperm count on AAS, alcohol and nicotine treatment which may be one of the contributing factors in male infertility.
Authors: Sravonee Purkayastha, Rita Mahanta
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1563369033