Year: 2009
Type: dissertation
Abstract: Development of multicellular organisms is a dynamic process that requires cellcell communication through the transmission of signal transduction pathways.Signaling cascades elicit transcriptional programs to synchronize discrete biological processes to pattern a multicellular organism.These signals are tightly regulated and their deregulation can lead to cancer onset and progression.Homeodomain interacting protein kinases (Hipks) represent a family of serine/threonine kinases.Members of this group (in particular Hipk2) have been implicated as important factors in transcriptional regulation to control cell growth, apoptosis and development.These studies identified an essential requirement for the sole v
Source: Summit (Simon Fraser University)
Author: Wendy Lee
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W156564022