Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation.
Year: 2014
Type: article
Abstract: Microtubule Affinity-Regulating Kinase 2 (MARK2) protein has a substantial role in regulation of vital cellular processes like induction of polarity, regulation of cell junctions, cytoskeleton structure and cell differentiation. The abnormal function of this protein has been associated with a number of pathological conditions like Alzheimer disease, autism, several carcinomas and development of virulent effects of Helicobacter pyloriββαβββ
Source: PubMed Central
Authors: Sajjad Ahrari, Navid Mogharrab
Institution: Shiraz University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1566183403