Work

The Control of Ribonucleic Acid Synthesis in Escherichia coli

Year: 1969

Type: article

Abstract: Stringent strains of Escherichia coli are shown to produce one, and usually two, 32P-labeled compounds specifically in response to amino acid starvation. This pattern of labeling is not observed in three derived relaxed strains. Comparison of properties of the system regulating the synthesis of these compounds with those of the amino acid control of RNA biosynthesis suggests that the unusual compounds participate in an early step in the mechanism which leads to the slowing of RNA biosynthesis during amino acid starvation of stringent strains.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(18)93106-6

Author: M Cashel

Institutions: National Institutes of Health, National Institute of Neurological Disorders and Stroke

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1568532879

FWCI: 13.83

Cites: 28

Cited by: 449

Related to: 10