ELISA in the diagnosis of Wuchereria bancrofti infection in man: a technique for reducing cross-reactivity.
Year: 1980
Type: article
Abstract: The cross-reactivity of filarial heteroantigens, the non-availability of adult Wuchereria bancrofti for antigen extraction, and the lack of structural information on purified filarial heteroantigens make the serological diagnosis of W. bancrofti infection in man a difficult problem. The use of immune sera from cattle infected with Setaria digitata when carrying out the enzyme-linked immunosorbent assay (ELISA) largely eliminated the cross-reactions with serum antibodies generally seen in subjects showing no evidence of W. bancrofti infection.
Source: Europe PMC (PubMed Central)
Authors: S Dissanayake, M M Ismail
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1570237630