Work

[New antiarrhythmic agents in atrial fibrillation].

Year: 2007

Type: article

Abstract: The convenience to count with a safe and effective pharmacological wealth for atrial fibrillation treatment had conduced, in a way, to a deep depuration of the vast array of antiarrhythmic drugs, keeping only a very restricted number of compounds with a widely proved anti-atrial activity. On the other hand, it had lead to the discovery of the pathophysiological concepts that point to novel therapeutic targets. Within these objectives is that new antiarrhythmic drugs with preferential, even selective, activity on myocardial atrium ion channels had been developed. Among these new antiarrhythmics, dofetilide, and AVE0118, are taken into account. In addition, new possibilities are opened based on the knowledge of the cardioprotective-antiarrhythmic qualities of the opioidergic system.

Source: PubMed

Authors: Gustavo Pastelín Hernández, Pastor Luna Ortíz, Fermín Alejandro Tenorio López, Leonardo del Valle Mondragón

Institution: Instituto Nacional de Cardiología

Language: Spanish

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W182160427

FWCI:

Cites: 8

Cited by: 1

Related to: 10