Work

Progressive aphasia: Patterns of language behavior and regional cortical atrophy

Year: 2009
Type: dissertation
Study design: Observational Study
Abstract: Individuals with progressive aphasia may demonstrate impairments of syntax, semantics, phonology, and orthography, and can provide important insight into the role of specific cortical regions in these language processing domains. In this study, eleven individuals with progressive aphasia underwent comprehensive language testing and structural MRI scanning. Voxel-based morphometry was used to examine the relation between cortical atrophy and behavioral measures. Results confirm the critical role of left perisylvian cortex for phonological processes involved in spoken and written communication and also for syntactic processing, whereas left temporal regions are critically involved in semantic processing common to spoken and written language.
Language: English
Open Access status: green
OpenAlex ID: W1572222525
Cites: 141
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Related to: 10