Work

Computer programs for multilocus haplotyping of general pedigrees.

Year: 1995

Type: article

Abstract: We have recently developed and implemented three different computer algorithms for accurate haplotyping with large numbers of codominant markers. Each of these algorithms employs likelihood criteria that correctly incorporate all intermarker recombination fractions. The three programs, HAPLO, SIMCROSS, and SIMWALK, are now available for haplotying general pedigrees. The HAPLO program will be distributed as part of the Programs for Pedigree Analysis package by Kenneth Lange. The SIMCROSS and SIMWALK programs are available by anonymous ftp from watson.hgen.pitt.edu. Each program is written in FORTRAN 77 and is distributed as source code. 15 refs.

Source: PubMed Central

Authors: D E Weeks, E Sobel, J R O'Connell, K Lange

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Human Genome Research Institute, National Cancer Institute

Awards: NOVEL ALGORITHMS FOR GENETIC MAPPING, Cancer Center Support Grant

OpenAlex ID: W1573179356

FWCI: 2.472

Cites: 12

Cited by: 150

Related to: 10