Comparison of Serum Lipids, Lipoproteins and Apolipoproteins in Patients Undergoing Cabg With Healthy Adults
Year: 2012
Type: article
Study design: Observational Study
Abstract: OBJECTIVE:To assess the pattern of plasma lipoproteins in CAD patients including comparison between diabetic andnon-diabetic subgroups.METHODS:This case control study was conducted at National Institute of Cardiovascular Diseases (NICVD) Karachi onpatients admitted for CABG from June, 2000 to June, 2001. A total of 100 patients and 100 healthy subjectswere enrolled during the study. 38 patients (38%) were diabetic with mean age of 46.16 years and 62 patients(62%) were non-diabetic with mean age of 45.26 years. Serum lipids, apolipoproteins A, apolipoproteins Band Lp(a) of each subject were analysed. One way ANOVA and 95% confidence interval for mean wereapplied to find the association of CAD with age, BMI, glucose, cholesterol, triacylglycerols, HDL-c, LDL-c,and Lp(a).RESULT:CABG patients had significantly higher blood TAG levels than controls. Similar results were observed forHDL-c, which was significantly lower when compared with control subjects. Apo-B and Lp(a) in controlswere significantly lower than both diabetic and non-diabetic CAD patients. The level of Apo-B in diabeticCAD was significantly higher when compared with control subjects.
Source: Pakistan Heart Journal
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1573555599