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MLN4924 induces Noxa upregulation in acute myelogenous leukemia and synergizes with Bcl-2 inhibitors

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Year: 2015
Type: article
Source: Cell Death and Differentiation
DOI: 10.1038/cdd.2015.74
Authors: K L B Knorr, P A Schneider, X W Meng, H Dai, B D Smith, A D Hess, J E Karp, S H Kaufmann
Institutions: Mayo Clinic, Johns Hopkins University
Language: English

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Mayo Clinic, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: G1165598027, G1357033417, G2268222605, G267304645, Phase I Clinical Trials of New Anti-Cancer Targeted Therapies, G2809363847, Cytotoxicity of MLN4924 in Acute Myeloid Leukemia, G6312026533, G883206123, G9000015799, G9000126810, G9000180826, Mayo Clinic Comprehensive Cancer Center Support Grant, Medical Scientist Training Program at Mayo Clinic
OpenAlex ID: W1574166501
FWCI: 2.572
Cites: 61
Cited by: 97
Related to: 10
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