Work

The collaborative study on the genetics of alcoholism: an update.

Year: 2002

Type: article

Abstract: Alcoholism (COGA) is a large-scale family study designed to identify genes that affect the risk for alcoholism (i.e., alcohol dependence) and alcohol-related characteristics and behaviors (i.e., phenotypes1). This collaborative project is funded by the National Institute on Alcohol Abuse and Alcoholism. Data collection, analysis, and/or storage for this study take place at nine sites across the United States. Because alcoholism is a complex genetic disorder, the COGA researchers expected that multiple genes would contribute to the risk. In other words, there will be no single “gene for alcoholism ” but rather variations in many different genes that together, interacting with the environment, place some people at significantly higher risk for the disease. This genetic and environmental variability (i.e., heterogeneity) makes the

Source: Europe PMC (PubMed Central)

Author: Howard J Edenberg

Institutions: Indiana University Indianapolis, Indiana University School of Medicine, Indiana University – Purdue University Indianapolis

Language: English

Topic: Genetic Associations and Epidemiology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Washington University in St. Louis, University of Connecticut, National Institute on Alcohol Abuse and Alcoholism

Award: COLLABORATIVE STUDY ON THE GENETICS OF ALCOHOLISM