Molecular basis of human obesity - literature review
Year: 2013
Type: article
Abstract: Obesity has become a serious health problem as well as economic and social chal lenge in the highly developed societies. In 201 0 there were over 1 bil l ion overweight people worldwide and ca. 475 mil l ion were classified as obese with the BMI ≥ 30. That global health problem became an alarming issue affecting developed and developing countries al ike. Genetic factors are attributed a special role in the etiopathogenesis of obesity. Recent data suggest that mutations and polymorphism identified in various genes contribute to a higher predisposition to obesity. In this review, we focus on the human monoand polygenic obesity syndromes. The purpose of this work is to present, based on the l iterature review, the most recent findings concerning genetic causes of obesity.
Authors: Tomaszewska, Agata, KopczyÅski, PrzemysÅaw, Flieger, RafaÅ, Thielemann, Anna
Institution: Poznan University of Medical Sciences
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W1578327529