Inhibition of Glucosyltransferase Activity by Antisera to Known Serotypes of Streptococcus mutans
Year: 1973
Type: article
Abstract: Using a recently developed assay for glucosyltransferase activity based on (14)C-glucose incorporation into an alcohol-insoluble polysaccharide, we were able to study inhibition by antibody of this enzyme activity. Rabbit antibody was relatively specific for the strain of Streptoccus mutans from which the enzyme was obtained. Absorption studies showed that neither removal of antibodies directed to dextran nor absorption with intact bacteria offset the enzyme-inhibitory capacity of these sera, whereas absorption with partially purified enzyme did result in removal of the inhibitory capacity.
Source: Infection and Immunity
Authors: R. T. Evans, R. J. Genco
Institution: University at Buffalo, State University of New York
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W1582188794