Effect of Diet Supplementation with Some Food Industry by- products on Cholesterol Levels of Rats
Year: 2015
Type: article
Abstract: Effect of food industry by-products orange peels, peanut skin peels and pomegranate peels on cholesterol level was investigated using sixty male adult Sprague-Dawely rats weighing 125 ± 5g. The negative control group of rats was fed on basal diet while the other sub-groups (positive groups) were fed on basal diet and the cholesterol diet (which was prepared by replacing 5% corn oil by cholesterol) together with various formulations of food by-products; orange peels, peanut skin and pomegranate peel. Total cholesterol and triglycerides decreased significantly (P<0.05) when rats fed on basal diet containing high doses of the food by-products. The total cholesterol and triglycerides levels pronouncedly decreased in rats fed on 10% peanut skin (100.34 ± 3.62 and 43.4 ± 4.94), respectively followed by 5% peanut skin (125.73 ± 3.09 and 46.24 ± 4.63). The serum HDL-C decreased significantly (P<0.05) in (control +) that fed on hypercholesterolemic diet (28.38 + 5.33), compared with healthy rats (control - ) that fed on basal diet (60.58 ± 3.62). The highest mean values of the ratio between LDL -C/HDL-C for tested groups were observed in the group fed on hypercholesterolemic diet containing 5%, followed by 7.5%, l0% pomegranate peel and 5% peanut skin. While, the lowest mean values of was observed in the group fed on basal diet containing the orange feed level 7.5%.
Source: Food and public health
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W158401591