Work

Challenges in IPF diagnosis, current management and future perspectives.

Year: 2015

Type: article

Abstract: Recent developments have clarified our understanding of IPF and improved outcomes with two viable new therapeutic options, pirfenidone and nintedanib. In spite of these advances, questions and challenges concerning IPF still remain. Here we will focus on some of these unresolved areas: the diagnosis of IPF is hindered by limitations in current practice guidelines, surgical lung biopsy is contraindicated in many patients, the accuracy of prognostic evaluation needs to be increased and tolerability factors can jeopardise adherence to treatment. We will also identify new developments shaping the future of IPF management such as cryobiopsy, increased understanding of genetic factors and new treatment paradigms, which may help to fulfil currently unmet needs.

Source: Sarcoidosis vasculitis and diffuse lung diseases

Authors: Athol U Wells, Ulrich Costabel, Venerino Poletti, Bruno Crestani, Jim Egan, George Margaritopoulos, Katerina Antoniou

Institutions: Royal Brompton Hospital, Ruhrlandklinik, Essen University Hospital, Ospedale G.B. Morgagni - L.Pierantoni, Hôpital Bichat-Claude-Bernard, Université Paris Diderot, Mater Misericordiae University Hospital, University of Crete

Language: English

Topic: Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W1585826760

FWCI: 1.861

Cites: 31

Cited by: 17

Related to: 10