Year: 1999
Type: article
Abstract: Genome scans for alcoholism susceptibility genes were carried out using identity-by-descent-based statistics for qualitative traits. We compared the results when 1) multipoint information was used for all families, where some had to be truncated, 2) multipoint information was used only for small families while large (untruncated) pedigrees were analyzed with a single-point approach, and 3) single-point analysis was used for all pedigrees. Differences between the methods were observed, but neither method could identify regions related to the susceptibility for alcoholism.
Source: Genetic Epidemiology
Authors: Sabine Loesgen, Michael Scholz, Silke Schmidt, Heike Bickeböller
Institutions: Technical University of Munich, German Cancer Research Center
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W1590680932