Work

Targeting the Warburg effect for leukemia therapy: Magnitude matters.

Year: 2015

Type: article

Abstract: Non-oxidative glucose metabolism represents a hallmark of cancer. It is now apparent that different cell states among normal stem or progenitor cells have distinct aerobic glycolysis (AG) dependencies. However, malignant cells are markedly more vulnerable to modifications of AG regardless of the differentiation state of their cell of origin.

Source: Europe PMC (PubMed Central)

DOI: 10.4161/23723556.2014.981988

Authors: Ying-Hua Wang, David T Scadden

Institutions: Harvard University, Massachusetts General Hospital, Harvard Stem Cell Institute

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1593765193

FWCI: 0.331

Cites: 10

Cited by: 10

Related to: 10