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Clofarabine Targets the Large Subunit (α) of Human Ribonucleotide Reductase in Live Cells by Assembly into Persistent Hexamers

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Year: 2012
Type: article
Source: Chemistry & Biology
DOI: 10.1016/j.chembiol.2012.05.015
Authors: Yimon Aye, Edward J. Brignole, Marcus J.C. Long, Johnathan Chittuluru, Catherine L. Drennan, Francisco J. Asturias, JoAnne Stubbe
Institutions: Massachusetts Institute of Technology, Scripps Research Institute, Howard Hughes Medical Institute, Brandeis University
Language: English

Topic: Biochemical and Molecular Research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Howard Hughes Medical Institute, Damon Runyon Cancer Research Foundation, National Institutes of Health, National Institute of General Medical Sciences, National Center for Research Resources
Awards: National Resource for Automated Molecular Microscopy, G1420030754, G3335494842, G6382528889, Ribonucleotide Reductases_Structure and Function, National Resource for Automated Molecular Microscopy, G9000090057, Structural studies of eukaryotic transcription
OpenAlex ID: W1593962234
FWCI: 1.022
Cites: 34
Cited by: 51
Related to: 10
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