Work

Non- and semi-parametric analysis of failure time data with missing failure indicators

Year: 2007
Type: book-chapter
Abstract: <!-- *** Custom HTML *** --> A class of estimating functions is introduced for the regression parameter of the Cox proportional hazards model to allow unknown failure statuses on some study subjects. The consistency and asymptotic normality of the resulting estimators are established under mild conditions. An adaptive estimator which achieves the minimum variance-covariance bound of the class is constructed. Numerical studies demonstrate that the asymptotic approximations are adequate for practical use and that the efficiency gain of the adaptive estimator over the complete-case analysis can be quite substantial. Similar methods are also developed for the nonparametric estimation of the survival function of a homogeneous population and for the estimation of the cumulative baseline hazard function under the Cox model.
Language: English
Open Access status: bronze
OpenAlex ID: W1594420653
FWCI: 8.385
Cites: 20
Cited by: 30
Related to: 10