Work

Lymphocyte-facilitated infection of epithelia by human T-cell lymphotropic virus type I

Year: 1992

Type: article

Abstract: After the addition of human T-cell lymphotropic virus type I (HTLV-I)-infected lymphocytes to enterocyte monolayers, the lymphocytes adhered via microvilli from both cell types and shed virus onto the enterocyte surface. Virus fused with the epithelial membrane and infected these cells as confirmed by electron microscopic immunocytochemistry, in situ hybridization, and amplification by polymerase chain reaction.

Source: Journal of Virology

DOI: 10.1128/jvi.66.7.4601-4605.1992

Authors: V R Zacharopoulos, M E Perotti, D M Phillips

Institution: Population Council

Language: English

Topic: T-cell and Retrovirus Studies

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development