Work

Solving Hodgkin-Huxley equations using the compact difference scheme - somadendrite

Year: 2013

Type: preprint

Abstract: Dendrites have voltage-gated ion channels which aid in production of action potentials. Thus dendrites are not just passive conductors of information, but actively act on the incoming input. Here we assume Hodgkin-Huxley formulations of voltage-gated ion channels on the dendrite. These equations are normally solved by some form of central difference scheme or the spectral methods. We use a compact finite-difference scheme to solve these equations. This scheme gives spectral-like spatial resolution while being easier to solve than spectral methods. The scheme has shown to be able to reproduce the results from spectral methods. In this paper cylindrical dendrites are described. It may also be noted that the compact difference scheme can be used to solve any other PDE both in biological as well as non biological systems. It is increasingly used in studying turbulence in airflow.

Source: arXiv (Cornell University)

DOI: 10.48550/arxiv.1308.1522

Authors: Gopinathan, Asha, Mathew, Joseph

Institutions: Sree Chitra Thirunal Institute for Medical Sciences and Technology, Indian Institute of Science Bangalore

Language: English

Topic: Differential Equations and Numerical Methods

Subfield: Numerical Analysis

Field: Mathematics

Domain: Physical Sciences

Open Access status: green

Funders: Indian Institute of Science, National Institute of Mental Health and Neurosciences, National University of Singapore, Department of Science and Technology, Ministry of Science and Technology, India, National Institute for Interdisciplinary Science and Technology

OpenAlex ID: W1597403754

Cites: 6

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Related to: 20