Work

Tissue Microarrays as a Tool in the Discovery and Validation of Tumor Markers

Year: 2009

Type: book-chapter

Abstract: Tissue microarrays are a platform of condensed histopathology that has revolutionized the translation of basic science to clinical utility. Tissue microarrays have resulted in a paradigm shift from histopathology to immunopathology and moved analysis of small selected samples sets of tens of specimens to a high-throughput environment of hundreds of specimens. Tissue microarrays have influenced validation strategies, but have a role in discovery as well, allowing a pathways approach to analysis of tumors.

Source: Methods in molecular biology

DOI: 10.1007/978-1-60327-811-9_11

Author: Stephen M. Hewitt

Institutions: National Institutes of Health, National Cancer Institute, Center for Cancer Research

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institutes of Health