Work

Glucocorticoid Receptors

Year: 1974

Type: article

Abstract: Specific glucocorticoid receptors from chick embryonic neural retina are demonstratable as early as 6 days in ovo. The receptor also binds progesterone with high affinity. Despite marked increases in glucocorticoid-provoked glutamine synthetase activity after Day 6, no increase in cytoplasmic receptor concentration occurs. Thus control of enzyme induction does not seem to depend simply on the presence of cytoplasmic steroid receptors but seems to be mediated by steps subsequent to the initial binding of hormone to receptor.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(20)79905-9

Authors: Marc E. Lippman, Barbara O. Wiggert, Gerald J. Chader, E. Brad Thompson

Institutions: National Institutes of Health, National Eye Institute, National Cancer Institute

Language: English

Topic: Estrogen and related hormone effects

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1602041200

FWCI: 4.057

Cites: 12

Cited by: 59

Related to: 10