Prevalence of metabolic syndrome in fathers of patients with polycystic ovarian syndrome
Year: 2010
Type: article
Study design: Observational Study
Abstract: Introduction: Women with polycystic ovarian syndrome (PCOS) have twice the risk for metabolicsyndrome as compared to women from the general population. Mothers and sisters of affected womenalso have an increased prevalence of metabolic syndrome. The aim of the study was to determine theprevalence of metabolic syndrome in fathers of patients with PCOS.Materials and Methods: 34 fathers of PCOS patients were evaluated. The control group was 34 fathersof normal women. The data were obtained from the clinical history and personal interview with thepatients, the controls and their fathers at Shiraz University of Medical Sciences in 2009. Prevalence ofmetabolic syndrome was determined according to Adult Treatment Panel index III (ATPIII) andInternational Diabetes Federation (IDF) criteria. Also incidence of hypertension and impaired glucosetolerance test, insulin resistance and diabetes type II were considered in both groups .Results: According to ATPIII and IDF criteria, the prevalence of metabolic disorders was 29.35% and41.17 in the fathers of the PCOS patients and 8.85% and 11.76 % in the fathers of the control group,respectively (p <0.008 and p<0.007, respectively). Also incidence of hypertension and impaired glcosetolerance test was significantly higher in fathers of the PCOS patients than control group (p< 0.05 .Conclusion: Our findings indicate that the fathers of women with PCOS have higher prevalence ofmetabolic syndrome and higher risk of developing hypertension and impaired glucose tolerance anddiabetes .
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1603306746