Molecular mechanism of fibrosis and central role of cardiotonic steroids in uremic cardiomyopathy.
Year: 2008
Type: article
Abstract: ……………………………………………………………………..…….……146 iv failure, was applied to the mouse, which we postulated would yield similar results.Employing this model, we show the relevance of Fli-1 in the negative regulation of collagen, thus revealing the molecular mechanisms by which cardiotonic steroids contribute to the cardiac fibrosis present in uremic cardiomyopathy.
Author: Jihad Elkareh
Institution: University of Toledo
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W160464328
