Topical Developments in High‐Field Dynamic Nuclear Polarization
Year: 2014
Type: article
Abstract: We report our recent efforts directed at improving high‐field dynamic nuclear polarization (DNP) experiments. We investigated a series of thiourea nitroxide radicals and the associated DNP enhancements ranging from ε=25 to 82, which demonstrate the impact of molecular structure on performance. We directly polarized low‐gamma nuclei, including 13C, 2H, and 17O, by the cross effect mechanism using trityl radicals as a polarization agent. We discuss a variety of sample preparation techniques for DNP with emphasis on the benefits of methods that do not use a glass‐forming cryoprotecting matrix. Lastly, we describe a corrugated waveguide for use in a 700 MHz/460 GHz DNP system that improves microwave delivery and increases enhancements up to 50 %.
Source: Israel Journal of Chemistry
Institutions: Massachusetts Institute of Technology, University of Florence
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
Awards: Advanced Instrumentation for Dynamic Nuclear Polarization NMR Research, Solid State NMR Studies of Peptides and Proteins, MIT/ Harvard Center for Magnetic Resonance, Innovative Instrumentation for High Magnetic Field DNP NMR, High Field DNP and EPR in Biological Systems, NMR Studies of Biological Membranes, Solid State NMR Studies of Membrane Proteins, Molecules for Dynamic Nuclear Polarization and NMR Structure Determination
OpenAlex ID: W1606424404