Work

Renal Transplantation and Urinary Proteomics

Year: 2012
Type: book-chapter
Abstract: Urine is the terminal metabolites of bloodstream which is produced by filtration of glomerulus, and re-absorption, secretion and excretion of the renal tubule and collecting tubule (Figure 1), so that proteins found in serum may also be identified in urinary proteins. Urinary composition and properties can reflect the status of the entire urinary system, especially the changes in the type and quantity of proteins in the urine that carry information of the occurrence and development as well as prognosis of a variety of diseases of the urinary system, urine can also reflect relevant situation of other organs of the body. The source of urine is simple, convenient and non-invasive, easily accepted by patients, with no discomfort and contraindications. Therefore, uroscopy is one of the most common and important methods used to diagnose kidney and urinary tract diseases. In this sense, urinary proteome analysis can be used for the diagnosis and / or prognosis indicators of diseases.
Language: English
Subfield: Spectroscopy
Field: Chemistry
Open Access status: hybrid
OpenAlex ID: W1606789862
FWCI:
Cites: 54
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Related to: 10