Clinicopathological evaluation of downer dairy cows with fatty liver.
Year: 2010
Type: article
Abstract: This study evaluated the relationship between severity of fatty liver and macromineral status in downer dairy cows and determined the usefulness of selected biochemical analytes for assessing prognosis. Blood and liver biopsy specimens were obtained from 36 Holstein downer cows shortly after the cows became recumbent and before they were treated. Liver tissue was examined histologically and serum activity of liver-derived enzymes and concentration of total lipids, triglycerides, bile acids, glucose, beta-hydroxybutyrate, acetoacetic acid, total bilirubin, non-esterified fatty acids (NEFA), cholesterol and macrominerals (Ca, Mg, K, Na, P) were determined. Fatty liver infiltration was severe in 44% of the cows and moderate in 44%. Serum activities of ornithine carbamoyltransferase and glutamate dehydrogenase, and NEFA/cholesterol ratio were good indicators of fatty liver. Cows with severe fatty liver had the lowest mean K values. The prognosis is guarded for downer cows with moderate and severe fatty liver and when total bilirubin concentration is high.
Source: Europe PMC (PubMed Central)
Authors: Emmanouil Kalaitzakis, Nikolaos Panousis, Nikolaos Roubies, Nektarios Giadinis, Eleni Kaldrymidou, Marios Georgiadis, Harilaos Karatzias
Institution: Aristotle University of Thessaloniki
Language: English
Subfield: Agronomy and Crop Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W160739680