Cell shrinkage follows, rather than mediates, the short-term effects of glucagon on carbohydrate metabolism
Year: 1992
Type: article
Abstract: The initial effects of glucagon on glycogen breakdown in isolated hepatocytes were found to be independent of cell volume and, when it occurred, cell shrinkage followed rather than mediated the glycogenolytic effect of glucagon. Similar conclusions could be drawn for the effect of glucagon on glycolysis/gluconeogenesis and for the antagonistic effect of insulin on glucagon action.
Source: Biochemical Journal
DOI: 10.1042/bj2870017
Authors: V Gaussin, A Baquet, L Hue
Institution: UCLouvain
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W1612758576