Future Research Directions in Asthma. An NHLBI Working Group Report
Year: 2015
Type: review
Abstract: Asthma is a common chronic disease without cure. Our understanding of asthma onset, pathobiology, classification, and management has evolved substantially over the past decade; however, significant asthma-related morbidity and excess healthcare use and costs persist. To address this important clinical condition, the NHLBI convened a group of extramural investigators for an Asthma Research Strategic Planning workshop on September 18-19, 2014, to accelerate discoveries and their translation to patients. The workshop focused on (1) in utero and early-life origins of asthma, (2) the use of phenotypes and endotypes to classify disease, (3) defining disease modification, (4) disease management, and (5) implementation research. This report summarizes the workshop and produces recommendations to guide future research in asthma.
Authors: Bruce D. Levy, Patricia J. Noel, Michelle M. Freemer, Michelle M. Cloutier, Steve N. Georas, Nizar N. Jarjour, Carole Ober, Prescott G. Woodruff, Kathleen C. Barnes, Bruce G. Bender, Carlos A. Camargo, Geoff L. Chupp, Loren C. Denlinger, John V. Fahy, Anne M. Fitzpatrick, Anne Fuhlbrigge, Ben M. Gaston, Tina V. Hartert, Jay K. Kolls, Susan V. Lynch, Wendy C. Moore, Wayne J. Morgan, Kari C. Nadeau, Dennis R. Ownby, Julian Solway, Stanley J. Szefler, Sally E. Wenzel, Rosalind J. Wright, Robert A. Smith, Serpil C. Erzurum
Institutions: Brigham and Women's Hospital, Harvard University, National Heart, Lung, and Blood Institute, UConn Health, University of Rochester, University of Wisconsin–Madison, UW Health University Hospital, University of Chicago, University of California, San Francisco, Johns Hopkins University, National Jewish Health, Massachusetts General Hospital, Yale University, Emory University, Case Western Reserve University, Vanderbilt University, University of Pittsburgh, Wake Forest University Health Sciences, Wake Forest University, University of Arizona, Stanford Medicine, Stanford University, Augusta University, Children's Hospital Colorado, University of Colorado Anschutz, Icahn School of Medicine at Mount Sinai, Cleveland Clinic Lerner College of Medicine
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1613323871