Reliability of flow-mediated dilation measures in the popliteal artery and implications for use in clinical and research practices
Year: 2012
Type: article
Abstract: PURPOSE: The aim of the present study was to assess the internal consistency and stability reliability of flow-mediated dilation (FMD) in the popliteal artery and to investigate the effect of occlusion pressure on the FMD response. METHODS: A series of FMD tests were performed on ten healthy young adult males to assess reliability. Ultrasound-derived artery diameter of the popliteal was measured and FMD was calculated as the percent change in diameter from baseline. RESULTS: FMD measurements for intra- and interday comparisons demonstrated poor reliability (Repeatability 5.62 and 4.82%, Intraclass correlation coefficient [ICC] 0.36 and 0.25, respectively). Repeatability values were as large as the FMD measures themselves for both intra- and interday reliability. CONCLUSION: Popliteal artery FMD has poor reliability for internal consistency and stability reliability. Interpretation of individual or group changes using this technique should be interpreted with caution.
Author: Kaitlin M. McLay
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W161346271