Work

Delayed growth in two German Shepherd Dog littermates with normal serum concentrations of growth hormone, thyroxine, and cortisol

Year: 1990

Type: article

Abstract: Four German Shepherd Dogs from a litter of 10 were evaluated because of postnatal onset of proportionate growth stunting that clinically resembled well-documented hypopituitary dwarfism in that breed. Although 2 pups had histologic evidence of hypopituitarism, the remaining 2 pups had normal serum growth hormone concentration and adrenocorticotropin secretory capability, and normal adrenal function test and thyroid function study results. Furthermore, the initially stunted German Shepherd Dogs grew at a steady rate until at 1 year, body weight and shoulder height approximated normal measurements. Seemingly, delayed growth in these pups may represent one end of a clinical spectrum associated with hypopituitarism in German Shepherd Dogs.

Source: Journal of the American Veterinary Medical Association

DOI: 10.2460/javma.1990.196.01.77

Authors: John F. Randolph, Christine L. Miller, John F. Cummings, Clinton D. Lothrop

Institutions: Cornell University, New York State College of Veterinary Medicine, University of Tennessee at Knoxville

Language: English

Topic: Growth Hormone and Insulin-like Growth Factors

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

Open Access status: bronze

OpenAlex ID: W161453571

FWCI:

Cites:

Cited by: 5

Related to: 10