Tratamiento del niño con talla baja en pubertad: rol de los inhibidores de la aromatasa
Year: 2006
Type: other
Abstract: HIGH DOSE GH A number of strategies have evolved in the last few years that attempt to increase height potential in growth retarded children who are in puberty. Since growth hormone (GH) production rates more than double during adolescence, the use of high-dose GH therapy has been studied in this period. In a randomized trial of conventional vs. high dose GH therapy for 36mo in GH deficient pubertal children we observed a significant increase in the adult height potential of the subjects in the high-dose group (net predicted height gain +4.9cm) as compared to conventional doses. This led to the US Food and Drug Administration approval of the use of higher GH doses in puberty in those kids most growth retarded during this period, or in those whose height potential is still quite limited and they are in puberty.
Source: Actualidad Contable FACES
Author: Nelly Mauras
Institution: Mayo Clinic
Language: Spanish
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W1619278637