Work

The Planar Organization of Lecithin-Cholesterol Bilayers

Year: 1972

Type: article

Abstract: The behavior of mixed phases of dipalmitoyl lecithin and cholesterol containing less than 33 mole per cent cholesterol has been followed by wide angle x-ray diffraction. Two phases are present in this region: a pure lecithin phase and a mixed phase of lecithin and cholesterol. We propose a model in which each cholesterol is surrounded by lipid hydrocarbon chains to describe the structure of the mixed phase.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)45196-x

Authors: Donald M. Engelman, James E. Rothman

Institution: Yale University

Language: English

Topic: Lipid Membrane Structure and Behavior

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W1644280525

FWCI: 4.795

Cites: 11

Cited by: 249

Related to: 10