Year: 2011
Type: article
Abstract: Free radicals are mainly formed under physiological conditions, for the incomplete reduction of molecular oxygen in oxidative metabolism, they are considered atoms or organic and inorganic molecules that have unpaired electron in their outer orbital, making them unstable and reactive with high capacity oxidant to biomolecules (lipids, carbohydrates, proteins and nucleic acids). Among the free radicals have nitric oxide (NO) required for enzymatic synthesis of L-arginine substrate, an oxygen atom and the presence of nitric oxide synthase (NOS).They play important roles in physiological processes such as regulation of vascular tone, modulation of sensory information transmission and immune effects but also participates in the pathogenesis of some chronic diseases of the oral cavity. The purpose of this study was to review which aims to investigate the influence of NO on the following diseases of the oral cavity, recurrent aphthous, pulpal pathology, oral cancer, chronic periodontitis and temporomandibular joint disorders, and found increased NO levels and NOS expression in these oral diseases.
Source: Acta Bioclínica
Institutions: Universidad de Los Andes, Universidad de Los Andes
Language: Spanish
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W1645673620