Work

Recent advances in neuroproteomics.

Year: 2007

Type: review

Abstract: The last few years have seen a rapid growth in the use of proteomic methods to study normal brain function. In addition, such methods have been used to analyze changes in protein expression associated with the onset and progression of neuronal disease. The field of neuroproteomics faces special challenges given the complex cellular and sub-cellular architecture of the central nervous system. This article presents a review of recent progress in studies of neuroproteomics, and highlights the strengths and limitations of current proteomic profiling technologies used in studies of neuronal protein expression.

Source: PubMed

Authors: Erika C Andrade, Dilja D Krueger, Angus C Nairn

Institution: Yale University

Language: English

Topic: Advanced Proteomics Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute on Drug Abuse

Awards: DRUGS OF ABUSE - ROLE OF PROTEIN PHOSPHORYLATION, Yale/NIDA Neuroproteomics Center